In the past, scientists thought that depression was the results of thoughts and emotions that were troubling in a person. Now, scientists have realized that there are severals aspects that workiin one's brain that can lead to depression. For example, then biological factor.
Biological causes are due to changes of chemistry in the brain, such as fluctations in the levels of important hormones. People usually have problems in the neurotransmitters, which are natural substances that allow that allow brain cells to communicate with eachother. Two of the transmitters that are implied in depression are serotonin and norepinephrine. Furthermore, deficiency in serotonin causes the sleeping problems, irritability, and anxiety. Likewise, a decreased amount of norepinephrine contributes to the fatigue and illness in depression.
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http://www.healthyplace.com/depression/main/causes-of-depression/menu-id-943/
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